Introduction
Garlic Butter Cajun Chicken with Cheddar Parmesan Penne is the perfect balance of spice, richness, and comfort. Tender Cajun-seasoned chicken brings smoky heat, while the penne is coated in a creamy cheese sauce made with sharp cheddar, nutty Parmesan, and fragrant garlic butter. This dish is ideal for family dinners, meal prep, or special occasions when you want something hearty yet crowd-pleasing.
Ingredient Breakdown & Why They Matter
🐔 For the Cajun Chicken
Chicken breasts – Lean, protein-rich, and perfect for absorbing bold Cajun flavors
Olive oil – Helps the seasoning adhere and promotes even browning
Garlic butter – Adds richness and aromatic depth
Cajun seasoning – Provides heat, smokiness, and Southern-inspired flavor
Paprika – Enhances color and adds mild sweetness
Salt & black pepper – Balances and sharpens the seasoning
🍝 For the Cheddar Parmesan Penne
Penne pasta – Holds creamy sauces well due to its ridges and hollow shape
Butter & garlic – The foundation of the sauce’s savory flavor
Flour – Thickens the sauce into a smooth, velvety consistency
Whole milk – Creates richness and creaminess
Cheddar cheese – Sharp, melty, and bold
Parmesan cheese – Adds depth and umami
Garlic & onion powder – Enhances the sauce without overpowering it
Step-by-Step Method of Preparation
- Season & Cook the Chicken
The chicken is tossed with olive oil and spices, then seared in garlic butter until golden and juicy. Cooking it first locks in flavor and creates tasty browned bits in the pan that enhance the sauce later.
- Cook the Pasta
Penne is boiled until al dente, ensuring it stays firm and doesn’t become mushy once mixed with the sauce.
- Build the Cheese Sauce
Butter and garlic form the aromatic base. Flour is whisked in to create a roux, which thickens the milk into a creamy sauce as it simmers.
- Melt the Cheeses
Cheddar and Parmesan are added slowly, creating a smooth, glossy sauce. Seasonings are adjusted to taste for balance.
- Combine & Finish
The pasta is tossed in the sauce, extra garlic butter is stirred in, and the Cajun chicken is layered on top for a bold finishing touch.
Flavor Profile
Creamy & Cheesy from the cheddar-Parmesan sauce
Savory & Garlicky thanks to butter and fresh garlic
Spicy & Smoky from Cajun seasoning and paprika
Comforting yet bold, making it both indulgent and exciting
Serving Suggestions
Garnish with fresh parsley or green onions
Serve with garlic bread or a crisp green salad
Add roasted vegetables like broccoli or bell peppers for balance
Storage & Reheating Tips
Refrigeration: Store in an airtight container for up to 3 days
Reheating: Warm gently on the stovetop or microwave with a splash of milk to loosen the sauce
Freezing: Not recommended, as cheese sauces can separate
Frequently Asked Questions (FAQ)
❓ Can I make this less spicy?
Yes! Reduce the Cajun seasoning by half or use a mild blend.
❓ Can I substitute the chicken?
Absolutely. Shrimp or turkey work well, and plant-based protein can be used for a vegetarian version.
❓ What if I don’t have penne?
Rotini, rigatoni, or fettuccine are excellent substitutes.
❓ Can I use pre-shredded cheese?
Freshly shredded cheese melts more smoothly, but pre-shredded works in a pinch—just stir slowly.
❓ How can I make it lighter?
Use low-fat milk, reduce butter slightly, or serve smaller portions with vegetables on the side.
Why This Recipe Works
This dish combines classic pasta techniques with bold Cajun flavors, resulting in a meal that feels both familiar and exciting. The balance of spice, creaminess, and texture makes it a reliable go-to recipe that satisfies a wide range of tastes.
Final Thoughts
Garlic Butter Cajun Chicken with Cheddar Parmesan Penne is more than just a pasta dish—it’s a comfort meal with personality. Whether you’re cooking for family, friends, or just yourself, it delivers rich flavor, satisfying texture, and unforgettable aroma in every bite. 🍗🧀🍝